The maintenance time of platelet transfusion is related to the freshness of platelet transfusion, and the general maintenance time of fresh platelet transfusion is about 7 days. Platelets are small pieces of cytoplasm shed from the cytoplasmic cleavage of skeletal mature megakaryocytes, which are extremely important for the body’s coagulation and hemostatic function, and can repair broken blood vessels. Platelets have a lifespan of about 7 to 14 days and are renewed at 1/10 of their total amount every day, so they usually last for about 7 days after receiving a transfusion of freshly collected platelets. The amount of platelets transfused and the cause of thrombocytopenia may also have a relationship with the maintenance time of platelets, e.g., patients with leukemia have a relatively short maintenance time after platelet transfusion. During the infusion process, it is necessary to pay attention to observe whether there is any allergic reaction or other abnormal reaction, if there is any abnormality, it should inform the doctor in time and carry out appropriate treatment under the doctor’s guidance. It is recommended to repeat the transfusion under doctor’s supervision.