Airway hyperreactivity may be caused by damage to the airway epithelium and intraepithelial nerves and allergen irritation.
Airway hyperreactivity means that the airways are more sensitive, which manifests as abnormal airway constriction when exposed to cold air or other allergens. While these factors may not be obvious or symptomatic for others.
Airway hyperreactivity may be related to genetic predisposition, or it may be caused by a combination of airway inflammatory mediators and cytokines that damage the airway epithelium and intra-epithelial nerves, etc. Symptoms such as coughing, wheezing, and dyspnea are usually present.
Viruses, drugs, cold air, bacteria, physical and chemical factors may make the airway hyperresponsive, causing airway constriction and spasm.
Airway hyperreactivity suggests that prompt medical attention is recommended to improve symptoms, and exposure to triggers should be avoided as much as possible during the day.