There are various causes of scrotal pain, which are commonly seen in orchitis and epididymitis, but also in scrotal trauma, varicocele, testicular torsion, and so on. 1. Orchitis: mostly caused by pathogenic bacteria infection, high fever, enlarged testicles, pain, scrotal swelling, reddened skin and swelling sensation can occur in orchitis. 2. Epididymitis: Epididymitis can be characterized by high fever, redness, swelling and pain in the scrotum, and some patients may have other symptoms such as nausea, vomiting, frequent urination and urinary urgency. 3. Scrotal trauma: If there is a history of trauma, scrotal pain may also occur. 4. Varicose veins of the spermatic cord: in severe cases of varicose veins of the spermatic cord, there will be pain in the scrotum, which will be aggravated by prolonged standing and exertion, and relieved by lying down, and varicose vein masses can be touched. 5. Testicular torsion: it can also manifest as severe pain in the scrotum. There are other reasons for scrotal pain, which should be treated in time.