The treatment of grade 2 CNS tumor is mainly based on surgery, combined with radiotherapy after surgery, which can achieve better therapeutic effect. Grade 2 CNS tumors can be treated by tumor resection surgery to remove the lesion and relieve obstructive hydrocephalus, after which radiotherapy can be carried out under the guidance of doctors, and ventriculoperitoneal shunt can be carried out to alleviate the situation of increased intracranial pressure. If the location where the surgery is needed is more complicated, or the patient’s physical tolerance ability is relatively poor and difficult to carry out the surgery, it can also be treated by stereotactic radiation therapy to improve the symptoms. Patients should go to the hospital in time after the appearance of CNS neuroblastoma. According to the professional doctor’s guidance and combined with personal situation, targeted treatment, to avoid blind use of drugs or delayed condition, resulting in adverse effects.