Muscle spasms in both lower limbs are seen in over fatigue, electrolyte deficiency, infectious diseases, neurological lesions and other diseases. 1. Excessive fatigue: such as too much exercise or strenuous exercise in a short period of time, it will cause muscle fatigue in the lower limbs, and when the fatigue reaches a certain level, spasm will occur. 2. Electrolyte disorders: for example, calcium deficiency, calcium deficiency will increase the excitability of the muscles, thus causing muscle spasm of both lower limbs. 3. Infectious diseases: for example, tetanus, encephalitis, etc. These are also prone to cause muscle spasm of both lower limbs. 4. Neurological lesions: such as epilepsy, cerebral hemorrhage, etc., which can cause abnormal brain discharges, and cause muscle spasms throughout the body. It can be seen that the causes of muscle spasms of both lower limbs are more reasons, you can go to the hospital to further identify the cause of the disease, and then targeted treatment.