The best time to measure blood pressure after taking oral antihypertensive medication depends on the type of antihypertensive medication and the individual patient’s condition, and cannot be generalized. In the case of short-acting antihypertensive drugs, it is recommended that the patient’s blood pressure be measured half an hour to one hour after taking the antihypertensive drug. If it is a long-acting antihypertensive drug, the effect is relatively slow and can be measured after 2 hours. If the patient’s blood pressure is currently stable and has been taking the medication for a period of time, the blood pressure can be measured at any time to spot check whether the current blood pressure status is stable. If necessary, patients are advised to have ambulatory blood pressure monitoring, which can assess the overall blood pressure situation over a 24-hour period. Especially for patients whose blood pressure remains unstable while taking antihypertensive medications, ambulatory blood pressure monitoring can be used to adjust the regimen of oral antihypertensive medications. In addition, patients with hypertension should pay attention to rest, eat a reasonable diet, maintain a relaxed mood, avoid anxiety and tension, and regularly review the changes in blood pressure.