The severity of submucosal elevated lesions in the esophagus is related to the nature of the elevated lesion. If it is inflammation-related or benign lesion such as smooth muscle tumor, it is generally not serious; if it is malignant lesion, it is more serious. 1. If there is inflammation in the esophageal mucosa, the bulge is caused by inflammatory stimulation, which is generally not serious, and can be cured after active anti-infection treatment. If the esophageal submucosal elevation is caused by other benign lesions, such as esophageal mucosal polyps, adenomas, smooth muscle tumors, hemangiomas, etc., it is generally not serious and can be cured after active endoscopic or surgical treatment. 2. If esophageal submucosal elevation is malignant and diagnosed as esophageal cancer by pathology, it is generally more serious and requires timely surgical treatment, chemotherapy or radiotherapy to prolong the survival period. Submucosal elevation of esophagus should go to hospital in time and be treated under doctor’s guidance.