Tofu scum discharge with itching may be a manifestation of lesions caused by vulvovaginal pseudomycosis. If a female patient develops diabetes mellitus, uses antibiotic drugs in large quantities for a long period of time, has a decreased immune function, or lives in a high temperature and high heat environment for a long period of time, this may lead to overgrowth of the fungus in the vagina and cause vulvovaginal pseudomicrobial yeast disease. The fungus causes significant damage to the vaginal mucosa and may cause symptoms such as tofu scum-like discharge and vaginal itching. If a female patient develops tofu scum-like discharge with itching, she needs to go to the hospital for routine gynecological examination and laboratory examination of secretions to make a clear diagnosis. The diagnosis of vulvovaginal pseudomycosis is usually confirmed when the spores or mycelium of Pseudomycetes are found in the smear of vaginal secretions. It is recommended to follow the doctor’s instructions to standardize drug treatment.