The reason for the skin on the hands is more, such as ringworm, hand eczema, exfoliative keratolysis, etc., need to find out the cause of the disease, according to the cause of the use of related drugs for treatment. 1. Ringworm: mainly caused by fungal infections of the skin, antifungal drugs can be used for external treatment, such as commonly used miconazole cream, clotrimazole cream, etc.; if the condition is more serious, external treatment is not good, oral antifungal drugs for systemic treatment, such as itraconazole, terbinafine. 2. Hand eczema: mainly caused by a variety of internal and external factors, can also lead to flaking and peeling of the hands, first of all, pay attention to good skin care, dry skin can be properly coated with hand cream, avoid the use of alkaline strong hand sanitizer or other stimuli. For patients with severe peeling, external glucocorticoid drugs can be used for treatment, such as halometasone, mometasone furoate, etc., can play a role in relieving. 3. Exfoliative keratolysis: a superficial exfoliative skin disease of the hands and feet, for patients with mild symptoms, appropriate moisturizers such as petroleum jelly ointment to moisturize and protect the skin; if the area of flaking is large, salicylic acid ointment can be applied to regulate the keratinization and reduce flaking. The use of specific drugs, need to be under the guidance of a professional doctor.