Generalized pain from colds may be related to the release of inflammatory factors due to the systemic immune response caused by viral infections; or it may be due to fever symptoms caused by colds, which leads to muscle tremors and excessive lactic acid production, causing soreness in the extremities. It can be treated by general treatment and medication (acetaminophen, ibuprofen, etc.). 1. General treatment: Patients with generalized cold and flu pains, those who are in serious condition or old and frail need to stay in bed, drink more water, and keep the air in the room circulating to prevent getting cold. 2. Medication: Under the guidance of the doctor, antipyretic and analgesic drugs such as acetaminophen and ibuprofen can be used, as well as cold and flu medicines such as phenmetrazine tablets. For immunodeficient patients with the common cold or influenza, antiviral treatment can be provided with drugs such as ribavirin and oseltamivir. Generalized pain can also be caused by other diseases. If the symptoms are not relieved or aggravated, patients are advised to go to the hospital in time, and under the guidance of the doctor, use the medication in strict compliance with the doctor’s instructions.