The interval between the third and second shots is related to the type of vaccine. The interval between the third and second shots of the common HPV vaccine is about 4 months, the interval between the hepatitis B vaccine and the second shot is 5 months, and the interval between the recombinant new coronavirus vaccine should be more than 4 weeks. 1. HPV vaccine: HPV vaccine requires a total of three shots and should be completed within 6 months, mainly including bivalent, quadrivalent and nine-valent three types of vaccine, of which the bivalent vaccine vaccination time point is 0-1-6 months, the third vaccine and the second shot interval is not more than 5 months, while the quadrivalent vaccine and the nine-valent vaccine vaccination time is 0-2-6, the third shot needs to be completed within 4 months after the second vaccination. The third vaccination needs to be completed within 4 months after the second vaccination. 2. Hepatitis B vaccine: generally, the vaccination will be carried out according to the program of 0-1-6 months interval, the first vaccination will be given within 24 hours after the birth of the child, then the second vaccination will be given in the first month after the birth, and then the third vaccination will be given in the sixth month after the birth, and the interval between the third and the second vaccination should not be more than 5 months. 3. Recombinant New Coronavirus Vaccine: Recombinant New Coronavirus Vaccine requires 3 doses, with an interval of more than 4 weeks between the 2 doses, of which the third dose needs to be completed within 6 months after the first dose. If it is not possible to receive the vaccination in time due to personal factors, then the vaccination should be done as soon as possible. If the vaccinated person needs to receive three shots of vaccine, then he/she should actively cooperate with the doctor’s arrangement and strictly follow the prescribed time for vaccination so as not to affect the effect of the vaccine.