Shoulder pain and inability to sleep can be caused by physiological reasons such as pillow fall, or pathological reasons such as frozen shoulder, cervical spondylosis, other shoulder joint diseases. 1. Physiological reasons: due to the incorrect sleeping posture, resulting in muscle tension and spasm at the shoulder, patients may have shoulder pain and can’t sleep. 2. Frozen shoulder: due to chronic aseptic inflammation of the soft tissues around the shoulder joint caused by long-term strain on the shoulder joint, patients may experience shoulder pain and sleeplessness. 3. Cervical spondylosis: due to cervical disc herniation, cervical spinal stenosis and other diseases that stimulate and compress the nerves of the upper limbs, patients may have shoulder pain and can’t sleep. 4. Other shoulder joint diseases: such as rheumatism, rheumatoid arthritis, shoulder joint tumor and other diseases, patients can have shoulder pain and can’t sleep. Shoulder pain and inability to sleep alone can not accurately determine the cause, but also need to be combined with the characteristics of the medical history, other test results to make an accurate judgment, it is recommended that the cause of the disease under the guidance of a doctor to clarify the cause of further treatment.