Prolonged dry cough can be seen in cough variant asthma, gastroesophageal reflux, chronic bronchitis, etc. It needs to be treated according to the etiology, including medication and lifestyle modification. Commonly used medications for cough variant asthma include inhaled glucocorticosteroids (e.g. budesonide), β2 agonists (e.g. salmeterol, salbutamol, etc.), and oral antiallergic drugs such as loratadine. For gastroesophageal reflux cough, commonly used drugs include acid suppressants (omeprazole) and prokinetic drugs (e.g. domperidone). It is important to adjust the diet to achieve a light diet and avoid stimulating foods. Commonly used drugs for chronic bronchitis are cough suppressants and phlegm removers (e.g. Ambroxol hydrochloride), and if there is a clear bacterial infection, antibiotics need to be applied for treatment, such as amoxicillin. Prolonged dry cough can also be seen in other diseases, it is recommended to consult a doctor in time, under the guidance of the doctor to use drugs, do not self-medication. The above medications should be used under the supervision of a physician.