Heart valve closure insufficiency, i.e., heart valve closure insufficiency, needs to choose the treatment plan according to the severity of closure insufficiency, which can be followed up for observation, symptomatic drug treatment, and in severe cases, surgery is needed, and active control of the primary disease is needed. Common heart valve closure insufficiency includes aortic valve closure insufficiency and mitral valve closure insufficiency. Common physiologic causes include degenerative heart valves; pathologic causes include rheumatic heart disease, papillary muscle rupture, dilated cardiomyopathy, long-term hypertension, myocardial infarction, and other conditions. If the degree of heart valve insufficiency is mild, it is a physiologic lesion and does not cause hemodynamic changes, so it can be followed up periodically for observation. If the degree of heart valve occlusion is more severe and the patient has recurrent symptoms such as chest tightness and dyspnea, symptomatic drug treatment is needed. Oral angiotensin inhibitors such as perindopril and fosinopril and diuretics such as furosemide can be prescribed to relieve clinical symptoms, and at the same time, treat the primary disease. Patients with poor cardiac function, severe valve regurgitation, and poor drug therapy are recommended to undergo surgical treatment with heart valve replacement. Patients with heart valve closure insufficiency should actively cooperate with the doctor’s treatment, maintain emotional stability in daily life, and avoid overwork to prevent increasing the burden on the heart.