Penile shortening is hereditary to a certain extent, but it does not necessarily mean that penile shortening is related to genetic factors, but may also be related to other factors such as circumcision and low testosterone levels. There are many causes of penile shortening, and genetic factor is one of the important causes, which can be accompanied by multiple deformities and related to chromosomal and genetic abnormalities. If the father, grandfather and other immediate family members have short penis, the probability of their offspring having short penis will be higher compared to normal people. In addition to genetic factors, there are many other causes of short penis. For example, a long foreskin will restrict the development of the glans, resulting in a short penis; if the testes atrophy due to infections, injuries, and fetal testicular torsion, resulting in a decrease in testosterone levels, a short penis will also occur. In addition to this, some of the causes of idiopathic penile shortening are still unknown. The causes of penile shortening are complex, and the presence of such a condition suggests prompt medical attention to confirm the diagnosis and early intervention in accordance with medical advice.