Craniopharyngiomas are benign tumors and usually do not metastasize. Craniopharyngioma is a slow-growing intracranial benign tumor of non-neuroepithelial origin in the saddle or parasaddle region, which is divided into glaucoma-forming type and papillary type, and different gene mutations may occur in different types, for example, CTNNB1 gene mutation is common in glaucoma-forming type, and BRAF V600E gene mutation is common in papillary type, which is of certain significance as a guideline for diagnosis and treatment. Benign tumors are defined as tumors without the ability to infiltrate and metastasize, and craniopharyngiomas are benign tumors, so metastasis does not usually occur. Similar to other benign tumors, craniopharyngiomas are often treated by surgical resection. Although craniopharyngiomas are benign tumors and generally do not metastasize, because of the deep location of craniopharyngiomas and the complexity of the surrounding adjacent structures, the rate of total surgical resection is low and there is a certain recurrence rate, so it is recommended that the patient should follow the doctor’s instructions for regular rechecking.