In general, muscle pain in the palm of the hand may be due to physiological causes, or due to trauma, myopathy, vascular lesions and other pathologic causes. 1. Physiological reasons Such as lifting heavy objects for a long time, lifting weights, etc., will cause discomfort and soreness in the hand muscles, which will lead to palm muscle pain, commonly found in porters, massage therapists and other people. Most of them can be improved after proper rest. 2. Pathological causes (1) Muscle lesions: muscle strain, contusion, inflammation, etc., can make the local tissue congestion, edema, pain is obvious. Severe cases may be accompanied by systemic symptoms such as fever and fatigue. (2) Vascular lesions: impaired blood circulation in the palm of the hand due to various reasons can lead to ischemia and hypoxia of the muscles in the palm of the hand, manifesting tingling, numbness and other discomforts. In addition, palm muscle pain can also be seen in other diseases, such as rest did not get better, it is recommended to go to the hospital in time to avoid delaying the condition.