Dizziness on the second day of hemodialysis may be caused by post-dialysis hypotension and imbalance syndrome. 1. Post-dialysis hypotension: due to the patient’s usual poor control of water intake and large amount of water removal in each dialysis, it leads to lowering of blood pressure and feeling of dizziness. Saline infusion can be carried out under the guidance of doctors, and human albumin can be used if necessary. 2. Imbalance syndrome: The rapid removal of metabolites trapped in the blood, including the rapid removal of solutes and the rapid correction of acidosis, etc., which causes cerebral edema and may lead to dizziness and other symptoms. It can be treated by intravenous mannitol, etc. on the advice of a doctor. There may be other reasons for dizziness on the second day of hemodialysis, so it is recommended that the patient go to the regular hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.