Stage I breast cancer with ki67 of 60% needs to go to the hospital for professional treatment (such as chemotherapy, endocrine therapy, targeted therapy, surgery, etc.), and after the operation, it is necessary to do the relevant recheck regularly. Generally speaking, the higher the marking rate of ki67 is, the more active the proliferation of cancer cells is, the higher the malignant degree is, and the more difficult it is to be completely cured, so it is necessary to carry out comprehensive treatment according to the overall situation of the patient, and at present, our country chooses the comprehensive treatment mainly based on surgery as the treatment method for breast cancer patients. 1. Drug therapy: chemical drug therapy (doxorubicin, paclitaxel, etc.), endocrine therapy (e.g. tamoxifen, anastrozole, etc.), targeted therapy (e.g. patuximab, trastuzumab, etc.). 2. Surgical treatment: including breast-conserving surgery, total mastectomy, etc. Sentinel lymph node biopsy, axillary lymph node dissection, etc. are chosen for axillary lymph node treatment. It should be noted that breast cancer patients can improve their prognosis through “early detection, early diagnosis and early treatment”, and many of them may survive for a long time, so it is recommended that patients build up their confidence in treatment and go to regular hospitals for consultation and treatment in time.