Cold cough in children is usually caused by acute upper respiratory tract infections, and commonly used oral medications include pediatric cough syrup, ibuprofen, and antibiotics. Acute upper respiratory tract infections are usually caused by a variety of pathogens such as rhinovirus, adenovirus, coronavirus and hemolytic streptococcal infections, common clinical manifestations include nasal congestion, runny nose, cough, sore throat and fever. Currently, ibuprofen and acetaminophen are given to relieve fever in children with cold cough, while pediatric cough syrup can relieve cough to a certain extent. For bacterial infections, antibacterial drugs such as cefaclor and cefdinir can be given. If a cold cough occurs in children, it is recommended to go to the pediatric internal medicine department as soon as possible to ensure a good prognosis for pediatric diseases. The above medications should be used under medical supervision.