Spinal cord thickening at the level of cervical 5~thoracic 1 vertebrae consider spinal cord edema or spinal cord tumor, etc. 1. Spinal cord edema: thickening of the ligamentum flavum at the level of cervical 5~thoracic 1 vertebrae and osteophytes cause compression of the spinal cord, resulting in spinal cord edema and degeneration, which is manifested as localized thickening. There may also be spinal cord edema caused by spinal trauma. You can follow the doctor’s instructions to apply dehydration and swelling drugs, such as sodium heptaphylloside, nutritive nerve drugs, methylcobalamin injection, conservative treatment is not effective in the line of decompression of the spinal plate neurolysis. 2. Spinal cord tumor: there are epidural tumors, including nerve sheath tumor, lipoma, metastatic tumor, intradural extramedullary tumors, including chordoma, nerve sheath tumor, neurofibroma, intramedullary tumors, including astrocytoma, ventricular meningioma, vascular reticulocytoma, which need to be diagnosed clearly through enhanced MRI film and surgical resection. Spinal cord thickening at the level of cervical 5~thoracic 1 vertebrae needs to be further examined in spinal surgery for clear diagnosis and further treatment.