Wake up at 5:00 in the morning left hand numbness may be a normal physiological phenomenon, may also be cervical spondylosis, carpal tunnel syndrome, cerebrovascular disease and other diseases caused. 1. Normal physiological phenomenon: the patient woke up in bed with numbness of the hand may be due to excessive pressure on one side of the limb before going to bed, long time inactivity, so that the local nerve root pressure caused by the general after a period of time can be restored, is a common normal physiological phenomenon, do not need to do special treatment. 2. Cervical spondylosis: If the patient himself suffers from cervical spondylosis, may also appear to sleep and wake up with numbness, usually because of cervical spondylosis is serious on the local nerve root compression caused by the numbness of the upper limbs, may also be accompanied by dizziness, neck and back pain, and so on. 3. Carpal tunnel syndrome: manifested as numbness or pain in the three fingers on the radial side, weakness in holding objects, especially in the middle finger, the worst symptoms at night or early in the morning, appropriate shaking of the wrist can be alleviated, and therefore, waking up from sleep can be numbness in the hand. 4. Cerebrovascular disease: cerebrovascular disease can lead to numbness of the limbs, and can occur at night, usually because of atherosclerosis. Therefore, you can sleep and wake up with numbness symptoms. Wake up at 5 o’clock in the morning when the left hand numbness, if the activity of the limbs after no relief, should be recommended to consult the hospital, clear causes, early treatment, so as not to delay the condition.