At present, there is no clear clinical indication for the time being that the third booster shot of New Crown injures the kidney. The safety and quality of the new crown vaccine currently applied in China have been clinically verified. However, a small number of patients receiving the third shot of New Crown vaccine may have adverse reactions, which may include localized redness, swelling, pain, and hard nodules. Systemic symptoms may also occur, including low-grade fever, loss of appetite, and malaise. These symptoms usually resolve on their own and do not require specific treatment. At present, there is no clear clinical indication for the time being that the New Crown Third Injection Booster will damage the kidneys. When you have finished the New Crown Third Injection Booster, you need to stay for 30 minutes, and if you have any serious adverse reactions, you should inform your doctor promptly and treat the symptoms quickly. If the patient’s discomfort is not relieved for more than three days after the third booster injection of the new crown, it is recommended to go to a regular hospital for consultation and treatment.