Gluteal injections are a common method of intramuscular injections used in clinical practice. When performing gluteal intramuscular injection, it is necessary to pay attention to the injection site, injection depth, and so on. 1. Injection site: the buttock is divided into 4 areas: upper outer, upper inner, lower outer and lower inner, usually choose the upper outer buttock area for intramuscular injection, the upper outer buttock area has less sciatic nerve passing through, and will not hurt the sciatic nerve. 2. Depth of injection: Sterilize the skin with iodophor, use a syringe to draw up the medicine and exhaust the air. Tense the skin with the left hand, take the syringe with the right hand, and pierce vertically into 2.5-3 centimeters. Pump the piston and observe whether there is blood return, inject the drug into the muscle when there is no blood return. After the gluteal injection is finished, use a dry cotton swab to press the entry point and pull out the needle quickly. Gluteal injections can injure the sciatic nerve if the injection is not properly positioned. If you need to have a gluteal injection, it is recommended to go to a local hospital to have a gluteal injection under professional medical staff to avoid adverse reactions.