Removing spots on the back of hands should be treated according to the causes, common causes are pigmentation, age spots, chloasma and so on, which can be treated by general treatment, medication, physical therapy and other measures. 1. Hyperpigmentation: first of all, keep the skin clean and hygienic, avoid contact with irritating chemicals, avoid direct sunlight, avoid scratching and stimulation, avoid physical stimulation such as friction, eat more fruits and vegetables rich in vitamins, and you can take medicines such as cumquatoside ointment, hydroquinone cream and other treatments, and you can also use lasers to remove them such as intense pulsed light. 2. Age spots: also known as seborrheic keratosis, related to sun exposure or skin aging, can be removed with the help of freezing or CO2 laser. 3. Melasma: you can use hydroquinone cream, azelaic acid cream and other drugs externally, which can regulate melanin metabolism and have a certain auxiliary effect on removing chloasma on hands, and you can also take photorejuvenation, strong pulse laser, Q-switched laser, picosecond laser and so on, which have a certain efficacy on removing spots. To remove the spots on the back of the hand, you need to go to the hospital for examination first and decide the specific treatment measures under the guidance of the doctor.