Thyroid nodule with mixed echogenicity grade III can be considered to be treated by conservative treatment, medication and surgery. 1. Conservative treatment: small lesions without clinical symptoms and normal thyroid function do not require treatment. Usually pay attention to adjusting the dietary structure, regular thyroid ultrasound and thyroid function tests. 2. Drug treatment: If accompanied by hyperthyroidism and symptoms of thyrotoxicity such as palpitation and anxiety, oral treatment with drugs such as propranolol and oral antithyroid drugs such as propylthiouracil can be used. Combined with hypothyroidism, oral levothyroxine sodium tablets to supplement thyroxine. The above drugs should be used under the guidance of a doctor. 3. Surgery: If the nodule grows gradually, compresses the trachea or has obvious respiratory difficulties, or if malignancy is considered, surgery can be chosen to remove the lesion. Mixed echogenic nodules of the thyroid gland should go to a regular hospital in time and be treated under the guidance of a doctor, do not use medication on your own, so as not to delay your condition.