Inflammation of the ear can cause headaches and sometimes swollen lymph nodes in the neck. It is recommended that the patient go to the hospital to improve the blood count and C-reactive protein to clarify the severity of the inflammation, and if the patient’s condition is serious, hospitalization may be considered for infusion treatment. Cephalosporin antibiotics, such as cefoperazone injection, cefuroxime sodium injection or cephalosporin pentahydrate injection, are more commonly used clinically, and patients need to do skin tests before using the drugs, and they cannot drink alcohol during the medication; patients with obvious headache can use loxoprofen sodium tablets for oral antipyretic and analgesic. During the treatment period, patients need to regularly review the blood routine and C-reactive protein, and regularly monitor the body temperature to clarify whether the inflammation index has a tendency to decrease. If there is no decrease, antibiotics need to be actively adjusted; if there is secretion from the external ear canal, the secretion can be sent for culture to clarify what antibiotics are more sensitive to and then actively adjusted.