Breast nodule grade 3 frequent stabbing pain may be caused by hormonal disorders during menstruation, inflammation and infection, malignant changes and other reasons. 1. Hormone disorders during menstruation: the mammary glands are affected by estrogen, and the body’s hormones during menstruation are prone to endocrine level disorders, which may stimulate the lobular tissue of the mammary gland, thus causing frequent stabbing pain in the mammary gland nodule level 3, which is often relieved after the end of the menstruation period. 2. Inflammation and infection: it may be due to breastfeeding milk stagnation, bacterial invasion, trauma and other reasons that lead to inflammation and infection of the mammary glands, usually with localized redness, swelling, frequent tingling and other symptoms, which may be accompanied by generalized fever, you can follow the doctor’s instructions to take acetaminophen, ibuprofen and other oral pain relief, you can also take amoxicillin, cephalexin, and other anti-infective treatments. 3. Malignant changes: breast nodule grade 3 still has a small possibility of malignant changes, so frequent stabbing pain, you should consult a doctor for examination, you can follow the doctor’s instructions through the breast ultrasound, breast magnetic resonance examination to understand the condition, if there is a malignant change to be operated immediately. Breast nodule grade 3 frequent stabbing pain should be immediately consulted, standardized treatment under the guidance of the doctor, regular review, but also pay attention to maintain good habits.