Low estradiol may be caused by ovarian failure or central nervous system, which may lead to endocrine disorders and delayed menstruation in women. Estradiol is a hormone secreted by female ovaries before menopause, which includes estrone and estriol in addition to estradiol, and low estradiol needs to be divided according to the situation. Low estradiol, follicle stimulating hormone and luteinizing hormone at the same time, luteinizing hormone withdrawal test can not come to menstruation, may be due to central nervous system disease; estradiol level is low, follicle stimulating hormone, luteinizing hormone, high, no menstruation for a long period of time, may be suffering from ovarian dysfunction. Low estradiol may cause endocrine disorders, leading to delayed menstruation and may affect the reproductive status of women. If symptoms of low estradiol appear, you should consult a doctor for timely treatment, pay attention to personal hygiene and develop good living habits.