Children aged 3 years and 4 months, Azithromycin can not be taken twice a day, need to follow the instructions strictly, otherwise it will affect its efficacy or side effects. Azithromycin is mainly used for the treatment of acute pharyngitis, tonsillitis caused by Streptococcus pyogenes; sinusitis, acute bronchitis, otitis media caused by sensitive bacteria; pneumonia disease caused by Streptococcus pneumoniae and Mycoplasma pneumoniae. Generally, Azithromycin is a tonic, i.e., taken once a day, 1 hour before or 2 hours after a meal. Azithromycin is not recommended to be taken twice a day. Taking it twice a day may lead to overdose of the drug and adverse reactions such as abdominal pain, nausea, vomiting, diarrhea, and rash. The drug is contraindicated for those who are allergic to azithromycin, erythromycin, macrolides and other drugs. It is recommended to use the drug under the guidance of a doctor, do not casually change the dosage of the drug, if there is any discomfort promptly go to the hospital for examination.