You will not get your period by taking estradiol valerate tablets, but only after you stop taking them. Estradiol valerate is an estrogen that is used to supplement the estrogen deficiency in a woman’s body. The onset of menstruation is when the estrogen and progesterone in a woman’s body drop before her period comes, and the endometrium loses hormonal protection thus shedding and bleeding occurs, so when you take estradiol valerate, you will not get your period because you are supplementing estrogen from outside. Estradiol valerate tablets are hormonal drugs and must be taken according to the course of treatment under the guidance of a doctor. Normally, menstruation will occur after you stop taking them for about twenty-one days. Because estradiol valerate tablets can treat a variety of diseases, it is still important to stop taking them according to medical advice.