There are currently two types of corkage, one is a 20 ml corkage and the other is a 100 ml called glycerin enema. The ingredients of these two preparations are different, but both are used to soften the stool. Usually, if you use a small bottle of corkage once, you can use two corkages depending on the patient. The mechanism is to soften the stool, stimulate the rectum and produce the feeling of defecation, adults who usually have serious constipation can use two enemas at a time is no problem. But for children, usually children only use half is 10 ml can be. And for the large open plug is glycerin enema once use one or half is enough, so use two open plug once, usually for adults small open plug 20 ml each of this form, for the more serious constipation of adults can use two.