Omeprazole can usually be discontinued straight away, but should be taken on the advice of a doctor, and the medication needs to be resumed if there is a worsening of symptoms. Omeprazole is indicated for gastric ulcers, stress ulcers, duodenal ulcers, Drei-Ahler syndrome and reflux esophagitis. At present, there is no clear discontinuation reaction after stopping the drug, you can try to stop the drug directly, if you find that the symptoms worsen after stopping the drug, you need to resume the original dose of the drug used, it is recommended to stop the drug according to the doctor’s instructions, if you feel unwell, go to the hospital for examination in a timely manner. Adverse reactions of omeprazole are usually mild and can disappear automatically, such as diarrhea, dizziness, headache, nausea and so on. The drug is contraindicated in people who are allergic to omeprazole, people with severe renal insufficiency and infants. The drug is not recommended for pregnant and lactating women. The drug needs to be used under the supervision of a doctor.