The difference between primary hypertension and secondary hypertension lies in the different causes of hypertension and treatment principles. 1. Etiology: the etiology of primary hypertension is still unclear, and it is generally believed to be caused by the interaction of genetic and environmental factors; while secondary hypertension is secondary to other diseases of hypertension, and the common diseases that cause secondary hypertension are: renal parenchymal diseases, renal vascular diseases, primary aldosteronism, pheochromocytoma, cortisolism and so on. 2. Treatment principle: there is no special treatment for primary hypertension, but only through drug control of blood pressure, commonly used drugs are nifedipine, amlodipine, etc. While controlling high blood pressure, actively treating the primary disease. Secondary hypertension needs to be treated by medication or surgery according to the cause of the disease. The above drugs should be used under the guidance of a doctor, and if any discomfort occurs, please consult the hospital in time to avoid delaying the condition.