If the hydronephrosis caused by kidney stones need to take surgical treatment, drug treatment, as well as general measures to regulate. 1. Surgical treatment: if the patient has hydronephrosis caused by kidney stones, and the diameter of kidney stones is 5~20mm, the patient can be treated by extracorporeal shock wave lithotripsy. For patients with stone diameter more than 20mm, they need to be treated by percutaneous nephrolithotripsy. In addition, if the diameter of kidney stone is less than 20mm, ureteroscopic lithotripsy can also be taken for treatment. 2. Medication: It is recommended that when patients with kidney stones and hydronephrosis experience pain, they can use non-steroidal anti-inflammatory drugs such as diclofenac sodium and indomethacin as prescribed by the doctor. Some patients can also be prescribed atropine, scopolamine and other antispasmodic drugs. For patients with concomitant infections, antibiotics such as cefixime and cefuroxime can be used under medical supervision. 3. General measures: patients with kidney stones accompanied by hydronephrosis should drink more water and can exercise properly every day. If patients have oxalate stones, they should eat less food rich in oxalate such as asparagus and spinach in their diet. It is recommended that patients with kidney stones with hydronephrosis need to consult a doctor in time, and the doctor will choose the appropriate measures for the treatment of the patient’s condition. The above drugs need to be used under the guidance of a professional physician, to avoid blind use of drugs, so as not to aggravate the condition.