Clinical ankylosing spondylitis is mainly treated by drugs (such as celecoxib, salazosulfapyridine, etanercept, etc.) and surgery. 1. Drug treatment: Ankylosing spondylitis often causes patients to experience back pain and other uncomfortable symptoms, so patients can take diclofenac sodium, celecoxib, meloxicam and other non-steroidal anti-inflammatory drugs as prescribed by the doctor to relieve. Some patients may also be prescribed anti-rheumatic drugs such as Liuzosulfapyridine, Methotrexate, Leflunomide, etc. in order to control the condition and improve the discomfort. Some patients may also apply tumor necrosis factor TNF-α antagonists such as etanercept and infliximab as prescribed by doctors. 2. Surgery: It is applicable to patients with serious condition, and the common clinical surgical methods include total hip replacement, spinal osteotomy, etc., which need to be judged according to the actual condition of the patients. It is recommended that patients with ankylosing spondylitis should consult the Rheumatology and Immunology Department in a timely manner and follow the doctor’s instructions for treatment, and should not use drugs or folk remedies indiscriminately on their own. Pay attention to daily rest, strengthen the lumbar back warmth, avoid overwork, cold.