A burst of tightness of the heart can be seen in normal people, can also be seen in coronary heart disease, neurosis, respiratory diseases, pleurisy, etc., the patient should consult a doctor in a timely manner, can use nitroglycerin, alprazolam and other treatments. 1. Physiological conditions: some people in strenuous exercise, emotional excitement or drink excitatory beverages, there will be a burst of heart tightening, generally stop the stimulus after the discomfort can disappear, without special treatment. 2. Coronary heart disease: insufficient blood supply to the coronary artery myocardial dysfunction, patients will have a burst of heart tightness, tachycardia and dyspnea and other symptoms, you can take clopidogrel, nitroglycerin and other drugs for treatment. 3. Neurosis: women are more common, especially in the more stressful people, there will be anxiety, fear, heart bursts of tightness and fear and other symptoms. Such people should maintain adequate sleep, appropriate physical labor, when necessary, the use of alprazolam, fluoxetine and other drugs for treatment. 4. Respiratory diseases: chronic obstructive pulmonary disease, bronchial asthma, pneumonia patients can also be caused by a lack of oxygen to the heart a burst of tightness, should be under the guidance of the doctor for appropriate treatment. 5. pleurisy: bacterial, viral and other factors caused by inflammatory lesions in the pleura, patients will have chest pain, respiratory depression, as well as hypoxia caused by a burst of tightness in the heart, can be treated with penicillin and other drugs. All of the above drugs should be used under the guidance of a doctor, and when discomfort occurs, active diagnosis and treatment are required.