Gray nails medically known as onychomycosis, is caused by fungal infections, may lead to thickening of the nail plate, there is no cure for onychomycosis nail plate thickening method, the treatment is mainly oral and topical antifungal drugs as the main, and can also be taken to the surgical treatment, if necessary. 1. medication: due to the thicker nail plate, it is difficult to penetrate the nail by simply applying topical medication, it is necessary to follow the doctor’s instruction to use oral antifungal medication and topical antifungal medication, such as oral fluconazole, itraconazole, terbinafine, etc., and at the same time, cooperate with topical antifungal medication, such as cyclobutrazolone nail coating, amorphophallus application, which can inhibit or kill the fungus. 2. Surgical treatment: when the effect of drug treatment is not good, you can also consider treatment through surgical way, through the extraction of nails to remove the diseased fingernails or toenails, after the surgery should pay attention to the prevention of infection. It is recommended that patients with onychomycosis pay attention to personal hygiene, increase the body’s immunity, and follow the doctor’s instructions to standardize treatment to prevent recurrence.