Lung adenocarcinoma cannot be operated because of the narrowing of heart blood vessels. It can be killed by radiotherapy, targeted therapy and immunotherapy. 1. Radiotherapy and chemotherapy: chemotherapy can effectively prevent cancer cells from spreading and metastasizing by giving drugs intravenously or orally, and commonly used drugs include platinum and so on. Radiotherapy treatment can avoid cancer cell metastasis and kill tumor cells locally by emitting rays through special instruments or equipment. 2. Targeted therapy and immunotherapy: targeted drugs can identify tumor cells with corresponding mutation targets and carry out targeted local treatment, but genetic testing is needed to determine whether they are suitable for targeted therapy, and commonly used drugs include gefitinib for EGFR mutation. Immunotherapy can enhance the patient’s anti-tumor immune function, commonly used drugs are pabolizumab and so on. It is recommended to go to the hospital for consultation and examination, formulate a personalized treatment plan according to the condition, and actively cooperate with the doctor for treatment.