The normal value of platelet count is (100-300)×10^9/L. Platelet count of 351×10^9/L is elevated, which may be caused by physiological elevation such as exercise rather than disease, but we can not exclude pathological elevation caused by disease such as infection. 1. Physiological increase: normal platelet count not only varies in the morning and afternoon of the day, but also is related to different seasons, different blood collection sites, female physiological period, pregnancy or not, and whether or not the activity. 2. Pathological increase: it can be secondary to myelodysplastic syndrome, acute infection, acute blood loss, acute hemolysis, after splenectomy, anemia after iron supplementation and other diseases. There are many reasons for high platelet count, in order to avoid delaying the condition, it is best to go to the hematology department of regular hospitals for professional diagnosis and treatment.