There is no authoritative literature on the fastest way to treat colic. Colic is related to physiological factors such as diet and spirituality, as well as pathological factors such as acute pancreatitis, acute appendicitis and cholelithiasis, which need to be relieved according to different causes. 1. Physiological factors: Bowel cramps caused by too much cold diet, overeating, mental stress, etc., you can use a hot towel or hot water bag to apply hot compresses to the abdomen, gently rubbing the abdomen while applying the hot compresses, you can get relief quickly. 2. Pathological factors: (1) Acute pancreatitis: it will cause stomach cramps, which usually need to be treated by applying antibiotics (e.g. cefrazole). (2) Acute appendicitis: it will have the symptom of metastatic right lower abdominal colic, which can be treated clinically by applying antibiotics (e.g. amoxicillin) for conservative treatment or surgical resection. (3) Cholelithiasis: it will lead to abdominal colic and usually requires lithotripsy. None of the above pathologic factors has a quick relief method, and all of them need to go to the hospital for early treatment under the guidance of the doctor. There are other pathological factors that cause abdominal cramps, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment, drugs should be used under the guidance of the doctor.