Scratchy little toe cracks are usually caused by fungal infection and ringworm. Because this part of the toe seam generally air circulation, coupled with frequent sweating, it is easy to harbor some fungi, fungal infection will have some inflammatory reaction. Usually manifested as some small pimples at the toe seam, mostly accompanied by itching sensation. In this case, you can use topical antifungal cream, such as sertaconazole nitrate cream, clotrimazole cream, etc. under the guidance and advice of the doctor. If necessary, it should be combined with oral antifungal drugs for systematic treatment, such as terbinafine tablets, itraconazole capsules. Meanwhile, pay attention to keep the toe joints cool and dry in daily life, and don’t wear damp and stuffy shoes to prevent the disease from recurring. Once itching occurs, some patients may not be able to resist scratching. If the skin is damaged, a bacterial infection may ensue. Itchy toe seams may also be other reasons, it is recommended that similar symptoms should be promptly regular hospital for standardized diagnosis and treatment.