Whether lupus nephritis type 4 can remain non-progressive for the rest of your life is related to factors such as your condition and the effectiveness of treatment. If the condition is mild and the treatment effect is good, the disease may not progress in the whole life; if the condition is severe and the treatment effect is poor, the disease may progress more quickly. Lupus nephritis is the kidney damage of SLE. More than 50% of SLE patients have kidney damage, and kidney biopsy shows almost 100% kidney involvement. Lupus nephritis is one of the major causes of end-stage renal failure in this country. If the disease is mild and is treated actively and effectively, it may not progress for the rest of its life, but it is prone to relapse after medication is reduced or discontinued, and the disease gradually worsens. If the condition is more severe and the treatment is not effective, the disease may progress and eventually develop into uremia. Patients with lupus nephritis type 4 are advised to go to regular hospitals in time and receive standardized treatment under the guidance of doctors.