Common early symptoms of acute cholangitis include abdominal pain, chills and high fever, and jaundice, which often flares up after eating fatty foods. The main causes of cholangitis are stone-induced bile duct obstruction, bile stasis, infection resulting in inflammatory reaction of the mucosa of the bile duct wall, congestion and edema of the bile duct wall leading to worsening of the obstruction, which in turn leads to a series of clinical symptoms such as abdominal pain, chills and high fever, jaundice and so on. Abdominal pain is often located in the lower part of the raphe and the right upper abdomen, with paroxysmal episodes, radiating to the back of the right shoulder, accompanied by nausea and vomiting; chills and high fever are often due to secondary infections, the bile duct obstruction causes the pressure in the bile duct to increase, and bacteria, toxins and other toxins can retrograde into the bloodstream, causing systemic infections; jaundice is due to the obstruction of bile ducts and the poor bile drainage, and the patient may have a deep yellow urine, yellowish skin, and so on. Acute cholangitis, if not actively treated, can rapidly progress to acute obstructive septic cholangitis, which can threaten the patient’s life in serious cases. Therefore, once the above symptoms appear, you should consult a doctor immediately, early treatment, so as to avoid the aggravation of the condition and the adverse consequences.