Pimples in medicine refers to acne, pimples next to the lips to consider and living habits, endocrine factors, skin cleaning is not in place and other factors. 1. Lifestyle habits: if the patient usually like to eat spicy stimulation, cake and other foods, it will stimulate the sebaceous glands around the lips to strengthen the function, and at the same time, for people who often stay up late at night, the sebaceous glands secretion of sebum at night increased, and easy to grow acne. 2. Endocrine factors: for women, if the androgen level is high, it will stimulate the sebaceous glands to secrete more oil, and if it blocks the mouth of the hair follicle, then it is easy to appear acne. 3. Inadequate skin cleansing: If the patient does not pay attention to makeup removal after make-up or the corner of the mouth skin cleansing is not in place, it is easy to lead to keratin, oil and other residues, breeding bacteria or fungi, but also easy to cause acne, folliculitis. For patients with acne next to the lips, it is recommended to go to the dermatology department of a regular hospital, to clarify the cause of the disease, and then actively treated under the guidance of the doctor.