Limited endometrial hyperplasia with large chunks coming out of oral dydrogesterone tablets on the fifth day of menstruation is an abnormal condition. The reasons for this are as follows: 1. endometrial lesions: endometrium if there is an abnormal lesion will appear hyperplasia symptoms, abnormal bleeding is recommended to go to the hospital as soon as possible to do a diagnostic scraping gynecology to determine whether the endometrial lesions, to exclude the abnormal lesions at the same time can play a role in stopping the bleeding. 2. endocrine disorders: exclude endometrial malignant lesions on the consideration of endocrine disorders, it is recommended that the second day of menstruation fasting blood test hormone six, according to the results of the hormone six test to determine the taking of supplemental Jiale, progesterone and other estrogen and progesterone sequential menstrual regulation treatment, need to go to the hospital obstetrics and gynecology under the guidance of the doctor regular use of medication, to avoid the use of medication to cause abnormal bleeding. The appearance of large blood clots need to pay attention to maintain vulvar hygiene, and at the same time relax, maintain a good state of mind, go to the hospital in a timely manner to seek medical treatment, by a professional doctor to give the relevant examination, in order to clarify the diagnosis, and for the cause of the treatment.