Enlarged and calcified lymph nodes in the chest may be caused by inflammation of the lungs, tuberculosis, lymphoma and so on. 1. Lung inflammation: chronic infectious diseases in the lungs, including pneumonia, lung abscess, chronic pulmonary fibrosis, etc., due to the existence of chronic inflammation, under the stimulation of inflammation, in the process of repair, it is easy to form enlarged lymph nodes and calcification, which usually indicates that the inflammation has been improved, and it does not need special treatment. 2. Tuberculosis: tuberculosis lymphadenitis caused by Mycobacterium tuberculosis infection, in the process of tuberculosis healing and repairing, calcium salt deposition leads to calcification of lymph nodes. Calcification of lymph nodes usually indicates that there are old lesions in the lungs, which suggests that they have been infected with Mycobacterium tuberculosis, and there are enlarged lymph nodes and calcification. 3. Lymphoma: malignant tumor of lymphocytes can lead to enlargement and calcification of lymph nodes in chest, accompanied by enlargement of lymph nodes in other parts of the body. If multiple lymph nodes are found to be enlarged, it is necessary to improve the blood routine, blood smear, puncture biopsy and other tests to make a clear diagnosis. There may also be other reasons for the increasing size of lymph nodes and calcification in the chest, so you should go to the hospital for treatment in time to prevent delaying your condition.