Transaminase 130U/L suggests that the transaminase is high, which may be caused by long-term staying up late and other bad habits, viral hepatitis, cirrhosis and other diseases. You can reduce transaminases by avoiding late nights and other lifestyle adjustments, taking drugs such as entecavir to treat the cause of the disease, and reducing glutathione and other drugs to reduce transaminases. 1. Lifestyle adjustments: Avoid prolonged overnight stays and overwork, etc., so that the body can get enough rest, which will help reduce transaminases. 2.Medication: (1) Reduced glutathione: it can participate in the cellular redox process, protect the sulfhydryl-containing enzymes and proteins in the liver cell membrane from being destroyed, and at the same time counteract the damage of free radicals to liver cells, achieve the effect of protecting liver cells and promoting repair, which can help to reduce the aminotransferase. (2) Dicyclanol: By scavenging free radicals, it can protect the integrity of liver cell membrane and reduce apoptosis of liver cells. Commonly used in chronic hepatitis, fatty liver, drug-induced liver damage caused by elevated transaminases. (3) Entecavir: Treatment should be directed at the cause of elevated transaminases, such as taking entecavir against hepatitis B virus. Transaminases of 130 U/L are recommended to consult a doctor in order to clarify the cause of the disease and carry out targeted treatment. In addition, all of the above drugs should be taken under the guidance of a doctor and should not be used without authorization.