Dry mouth and bitter mouth according to different causes, need to take different drugs, such as bile reflux patients can take ursodeoxycholic acid and other drugs, oral inflammation patients can take metronidazole and other drugs, specific as follows. 1. Bile reflux patients can take drugs to regulate gastric power, such as mosapride citrate, domperidone tablets, while taking drugs to regulate bile metabolism, such as ursodeoxycholic acid. 2. Oral diseases such as periodontitis, first of all, dental scaling, remove plaque and calculus, and then local medicine, acute or severe symptoms can be oral anti-inflammatory drugs, such as metronidazole tablets. If the mouth ulcers, more do not need to take drugs, pay attention to oral hygiene, local ice boron powder treatment. 3. Gastrointestinal diseases, such as chronic gastritis, gastric ulcer. Chronic gastritis patients with Helicobacter pylori infection can use quadruple therapy, such as rabeprazole enteric-coated tablets, amoxicillin, clarithromycin, colloidal bismuth pectin, etc.; patients with chronic gastritis, such as dyspepsia and other symptoms, you can take mosapride, domperidone and so on. Gastric ulcer patients can use cimetidine and other acid-suppressing drugs, magnesium aluminum carbonate chewable tablets and other gastric mucosa protectants. Dry mouth and bitter mouth may also be caused by other reasons, it is recommended to go to the hospital as soon as possible, after a clear diagnosis, follow the doctor’s prescription medication, to avoid blind use of drugs to cause adverse effects.