The treatment of chronic renal insufficiency is primarily a symptomatic regimen. It includes drug therapy (iron polysaccharide, nifedipine extended-release tablets, sodium bicarbonate, etc.), renal replacement therapy, etc. 1. Pharmacological treatment: erythropoietin, iron polysaccharides, roxarestat, etc. should be applied under the guidance of physicians to correct anemia; Benadryl, nifedipine extended-release tablets, etc. should be used to lower blood pressure; sodium bicarbonate tablets should be used to correct acidosis; lanthanum carbonate, calcium acetate, etc. should be used to improve calcium-phosphorus disorders; and cinacalcet, osteotriol, etc. should be used to correct secondary hyperparathyroidism. 2. Renal replacement therapy: when the level of uremia is reached, renal replacement therapy is needed, including hemodialysis, peritoneal dialysis, and kidney transplantation. Dialysis treatment can replace part of the kidney function, and the harmful substances produced in the body can be discharged out of the body in time. Kidney transplantation can generally reduce the blood creatinine level to normal, but need to take anti-rejection drugs (such as tacrolimus, cyclosporine, etc.) for a long time. When patients develop chronic renal insufficiency, it is recommended that they go to regular hospitals in time and under the guidance of doctors for treatment.